What is the catalog number for GDC-2992?

The catalog number for GDC-2992 is E8277-1mg.

What sizes are available for GDC-2992?

GDC-2992 is available in the following size(s): 1 mg.

Is GDC-2992 in stock?

GDC-2992 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures GDC-2992?

GDC-2992 is manufactured by Bimake.

What is the estimated delivery time for GDC-2992?

Estimated delivery time for GDC-2992 is approximately 15 business day(s), depending on your location.

GDC-2992

Product Specifications

CAS Number

2753651-10-2

Synonyms

RO7656594

Target

Androgen Receptor

Applications

Endocrinology & Hormones

Molecular Formula

C45H51ClN8O5

Additionnal Information

GDC-2992 (RO7656594, Compound 28A) is an orally active degrader of androgen receptor (AR) with a DC50 of 2.7 nM. It binds to AR and cereblon (CRBN), inducing AR ubiquitination and degradation. GDC-2992 also inhibits cell proliferation in VCaP cells and exhibits potential to reduce treatment resistance and disease relapse in prostate cancer.