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5-Ph-IAA

Product Specifications

CAS Number

168649-23-8

Target

Others

Applications

Others

Molecular Formula

C16H13NO2

Additionnal Information

The 5-Ph-IAA is a bumped-IAA analogue, that establishes the auxin-inducible degron 2 (AID2) system with the OsTIR1 (F74G) mutant, enabling precise, rapid degradation with 670-fold lower ligand concentration. It induces rapid and efficient depletion of mAID-fused proteins to study protein function in living cells, exhibiting significant tumor suppression properties.

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NEK8, NT (Never in Mitosis A-related Kinase 8, NimA-related Protein Kinase 8, JCK, MGC138445, Nima-related Protein Kinase 12a, NEK12A, NPHP9, Serine/threonine Protein Kinase Nek8) (MaxLight 650)
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