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Amiloride

Product Specifications

CAS Number

2609-46-3

Synonyms

MK-870

Target

Sodium Channel

Applications

Transmembrane Transporters

Molecular Formula

C6H8ClN7O

Additionnal Information

Amiloride (MK-870) is the first potent inhibitor of epithelial sodium channel (ENaC), inhibiting δβγ ENaC with an IC50 of 2.6 μM. It is also a typical blocker of PC2 (TRPP2) channels and can be used in the research to study Autosomal dominant polycystic kidney disease (ADPKD) .

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