Isosilybin A
Product Specifications
CAS Number
142796-21-2
Target
Apoptosis related
Applications
Apoptosis
Molecular Formula
C25H22O10
Additionnal Information
Isosilybin A is a flavonolignan isolated from silymarin that exhibits anti-prostate cancer (PCA) efficacy with an IC50 of 32 μM in DU145 cells. It induces growth inhibition, G1 arrest, and apoptosis in PCA cells by targeting the Akt-NF-κB-AR axis, highlighting its potential as a therapeutic agent in clinical prostate cancer (PCA) management.
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