2'-C-Methyladenosine
Product Specifications
CAS Number
15397-12-3
Target
HCV Protease
Applications
Proteases
Molecular Formula
C11H15N5O4
Additionnal Information
2’-C-Methyladenosine is an inhibitor of hepatitis C virus (HCV) replication, with an IC50 of 0.3 μM in Huh-7 cells. It is converted intracellularly to its triphosphate form (2’-C-methyladenosine triphosphate), which acts as a chain terminator and directly inhibits the HCV RNA-dependent RNA polymerase (NS5B) with an IC50 of 1.9 μM in enzymatic assays.
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