PYZD-4409
Product Specifications
CAS Number
423148-78-1
Target
E1 Activating
Applications
Ubiquitin
Molecular Formula
C14H7ClFN3O5
Additionnal Information
PYZD-4409 is a potent and specific small molecule inhibitor of the ubiquitin-activating enzyme UBA1 (E1) with an IC50 of 20 μM. It induces cell death in malignant cells and preferentially inhibits the clonogenic growth of primary acute myeloid leukemia cells and can be used as a research for developing treatments for hematologic malignancies.
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