ACY-957
Product Specifications
CAS Number
1609389-52-7
Target
HDAC
Applications
DNA Damage/DNA Repair
Molecular Formula
C24H23N5OS
Additionnal Information
ACY-957 is a selective chemical inhibitor of HDAC1 and HDAC2 with an IC50 values of 7 nM, 18 nM against HDAC1/2 respectively. It induces hemoglobin protein (HbF) in primary erythroid progenitor cells, including those from sickle cell patients, offering a promising approach for treating sickle cell disease (SCD) and β-thalassemia.
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