GW274150
Product Specifications
CAS Number
210354-22-6
Additionnal Information
GW274150 is a potent, selective, orally active and NADPH-dependent inhibitor of human inducible nitric oxide synthase (iNOS) (IC50=2.19 μM; Kd=40 nM) and rat iNOS (ED50=1.15 μM) . GW274150 also displays less potency for both humans or rats endothelial NOS (eNOS) and neuronal NOS (nNOS) . GW274150 exerts a protective role in an acute model of lung injury inflammation.
Storage Conditions
3 years-20°C powder 2 years-80°C in solvent
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