GNF4877
Product Specifications
CAS Number
2041073-22-5
Target
DYRK
Applications
Protein Tyrosine Kinase
Molecular Formula
C25H27FN6O4
Additionnal Information
GNF4877 is an aminopyrazine and a potent inhibitor of GSK3β and DYRK1A with an IC50 of 16 nM and 6 nM, respectively. It blocks nuclear factor of activated T-cells (NFATc) nuclear export, promotes β-cell proliferation, and is useful for research on diabetes drug development.
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