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7-Chlorokynurenic acid

Product Specifications

CAS Number

18000-24-3

Synonyms

7-CKA

Additionnal Information

7-Chlorokynurenic acid (7-CKA) is a potent and selective antagonist of the glycine B coagonist site of the N-methyl-D-aspartate (NMDA) receptor (IC50=0.56 μM) . 7-Chlorokynurenic acid is also a potent inhibitor of the reuptake of glutamate into synaptic vesicles with a Ki of 0.59 μM. 7-Chlorokynurenic acid has potent antinociceptive actions after neuraxial delivery.

Storage Conditions

3 years-20°C powder 2 years-80°C in solvent

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