VU 0240551
Product Specifications
CAS Number
893990-34-6
Additionnal Information
VU 0240551 is a potent neuronal K-Cl cotransporter KCC2 inhibitor (IC50=560 nM) and is selective versus NKCC1. VU 0240551 also inhibits hERG and L-type Ca2+ channels. VU 0240551 attenuates GABA-induced hyperpolarization of P cells, produces a positive shift in the P cell GABA reversal potential and enhances P cell synaptic transmission.
Storage Conditions
3 years-20°C powder 2 years-80°C in solvent
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