Taltobulin
Product Specifications
CAS Number
228266-40-8
Synonyms
HTI-286, SPA-110
Additionnal Information
Taltobulin (HTI-286), a synthetic analogue of the tripeptide hemiasterlin, is a potent antimicrotubule agent that circumvents P-glycoprotein-mediated resistance in vitro and in vivo. Taltobulin inhibits the polymerization of purified tubulin, disrupts microtubule organization in cells, and induces mitotic arrest, as well as apoptosis.
Storage Conditions
3 years-20°C powder 2 years-80°C in solvent
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