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Taltobulin

Product Specifications

CAS Number

228266-40-8

Synonyms

HTI-286, SPA-110

Additionnal Information

Taltobulin (HTI-286), a synthetic analogue of the tripeptide hemiasterlin, is a potent antimicrotubule agent that circumvents P-glycoprotein-mediated resistance in vitro and in vivo. Taltobulin inhibits the polymerization of purified tubulin, disrupts microtubule organization in cells, and induces mitotic arrest, as well as apoptosis.

Storage Conditions

3 years-20°C powder 2 years-80°C in solvent

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