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Pifithrin-α, p-Nitro, Cyclic

Product Specifications

CAS Number

60477-38-5

Synonyms

PFN-α

Additionnal Information

Pifithrin-α, p-Nitro, Cyclic (PFN-α) is cell-permeable and active-form p53 inhibitor. Pifithrin-α, p-Nitro, Cyclic is one order magnitude more active than Pifithrin-α in protecting cortical neurons exposed to Etoposide (ED50=30 nM) . Pifithrin-α, p-Nitro, Cyclic behaves as a p53 posttranscriptional activity inhibitor. Pifithrin-α, p-Nitro, Cyclic do not prevent p53 phosphorylation on the S15 residue.

Storage Conditions

3 years-20°C powder 2 years-80°C in solvent

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