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Zaprinast

Product Specifications

CAS Number

37762-06-4

Synonyms

M&B 22948

Additionnal Information

Zaprinast (M&B 22948) is a selective inhibitor of cGMP-selective Phosphodiesterase (PDE5) . Zaprinast causes a significant increase in cGMP levels in myocytes. Zaprinast is a G protein-coupled receptor 35 (GPR35) agonist which activates rat GPR35 strongly and activates human GPR35 moderately. Zaprinast reduces vessel remodeling through antiproliferative and proapoptotic effects.

Storage Conditions

3 years-20°C powder 2 years-80°C in solvent

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