Veliparib dihydrochloride
Product Specifications
CAS Number
912445-05-7
Synonyms
ABT-888 dihydrochloride
Target
PARP
Applications
DNA Damage/DNA Repair
Molecular Formula
C13H16N4O.2ClH
Additionnal Information
Veliparib dihydrochloride is an orally active and potent inhibitor of both PARP-1 and PARP-2 with Kis of 5.2 nM and 2.9 nM, respectively. It exhibit ability to cross the blood-brain barrier and potentiate DNA-damaging agents in preclinical tumor model.
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