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Cyclo (RGDyK)

Product Specifications

CAS Number

217099-14-4

Target

Integrin

Applications

Cytoskeletal Signaling

Molecular Formula

C27H41N9O8

Additionnal Information

Cyclo (RGDyK) is a potent and selective inhibitor of αVβ3 integrin . It significantly reduces lung inflammation and fibrosis induced by influenza A virus, and improves lung morphology, lowers pulmonary fibrosis scores, and suppresses the expression of αVβ3, TGF-β1, NF-κB p65, p38 MAPK, and HIF-1α, confirming its protective effects against ALI and pulmonary fibrosis.
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