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7β-Hydroxycholesterol

Product Specifications

CAS Number

566-27-8

Target

Immunology & Inflammation related

Applications

Immunology & Inflammation

Molecular Formula

C27H46O2

Additionnal Information

7β-Hydroxycholesterol is an oxysterol derived from the oxidation of cholesterol. It induces endothelial apoptosis, IL-1β secretion, and oxidative stress, leading to inflammation and organelle dysfunction. It also upregulates ICAM-1, VCAM-1, and E-selectin, thereby enhancing leukocyte adhesion in early atherosclerosis.

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