C16-Ceramide
Product Specifications
CAS Number
24696-26-2
Synonyms
N-Palmitoylsphingosine
Target
P53
Applications
Apoptosis
Molecular Formula
C34H67NO3
Additionnal Information
C16-Ceramide (N-Palmitoylsphingosine) is a sphingolipid ligand and an activator of p53 tumor suppressor. It tightly binds within the p53 DNA-binding domain with a Kd of ~ 60 nM, in close vicinity to the Box V motif. It regulates the protein ubiquitination and proteasomal degradation and also induces apoptosis in cancer cells making it a research tool for targeting human cancers.
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
orb700350 2 mg
Goat Human IgM (μ chain), Affinity purified, Unconjugated, min, cross-reactivity to human IgA+IgG Antibody
Sign In for Pricing
View Details 
MBS7015650-01 0.02 mg
Recombinant Equine herpesvirus 1 Envelope glycoprotein I (GI)
Sign In for Pricing
View Details MBS7015650-02 0.1 mg
Recombinant Equine herpesvirus 1 Envelope glycoprotein I (GI)
Sign In for Pricing
View Details