Rigosertib
Product Specifications
CAS Number
592542-59-1
Synonyms
ON-191
Additionnal Information
Rigosertib (ON-01910) is a multi-kinase inhibitor and a selective anti-cancer agent, which induces apoptosis by inhibition the PI3 kinase/Akt pathway, promots the phosphorylation of histone H2AX and induces G2/M arrest in cell cycle. Rigosertib is a selective and non-ATP-competitive inhibitor of PLK1 with an IC50 of 9 nM.
Storage Conditions
3 years-20°C powder 2 years-80°C in solvent
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