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Rigosertib

Product Specifications

CAS Number

592542-59-1

Synonyms

ON-191

Additionnal Information

Rigosertib (ON-01910) is a multi-kinase inhibitor and a selective anti-cancer agent, which induces apoptosis by inhibition the PI3 kinase/Akt pathway, promots the phosphorylation of histone H2AX and induces G2/M arrest in cell cycle. Rigosertib is a selective and non-ATP-competitive inhibitor of PLK1 with an IC50 of 9 nM.

Storage Conditions

3 years-20°C powder 2 years-80°C in solvent

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