What is the catalog number for PF-543?

The catalog number for PF-543 is E7015-5mg.

What sizes are available for PF-543?

PF-543 is available in the following size(s): 5 mg.

PF-543 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures PF-543?

PF-543 is manufactured by Bimake.

What is the estimated delivery time for PF-543?

Estimated delivery time for PF-543 is approximately 15 business day(s), depending on your location.

PF-543

Product Specifications

CAS Number

1415562-82-1

Synonyms

Sphingosine Kinase 1 Inhibitor II

Additionnal Information

PF-543 (Sphingosine Kinase 1 Inhibitor II) is a potent, selective, reversible and sphingosine-competitive SPHK1 inhibitor with an IC50 of 2 nM and a Ki of 3.6 nM. PF-543 is >100-fold selectivity for SPHK1 over SPHK2. PF-543 is an effective potent inhibitor of sphingosine 1-phosphate (S1P) formation in whole blood with an IC50 of 26.7 nM. PF-543 induces apoptosis, necrosis, and autophagy.