Cholesteryl hemisuccinate
Product Specifications
CAS Number
1510-21-0
Target
Topoisomerase
Applications
DNA Damage/DNA Repair
Molecular Formula
C31H50O4
Additionnal Information
Cholesteryl hemisuccinate is a cholesterol derivative and a potent inhibior of DNA polymerase and DNA topoisomerase with an IC50 of 2.9 μM, 6.3 μM, 25 μM for Rat DNA polymerase β, Human DNA polymerase λ and Human DNA topoisomerase I respectively. It exhibits anticancer effect due to its ability to inhibit DNA replication, repair and cell division and can be used in cancer cell growth research.
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