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Sulindac sulfide

Product Specifications

CAS Number

49627-27-2

Synonyms

Cis-Sulindac sulfide

Target

Secretase

Applications

Stem Cells & Wnt

Molecular Formula

C20H17FO2S

Additionnal Information

Sulindac sulfide is a potent, reversible and noncompetitive inhibitor of γ42-secretase with an IC50 of 20.2 μM. It preferentially reduces Aβ42 generation, inhibits Aβ40 and Notch intracellular domain production, and can be used in Alzheimer's disease research.

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