Sulindac sulfide
Product Specifications
CAS Number
49627-27-2
Synonyms
Cis-Sulindac sulfide
Target
Secretase
Applications
Stem Cells & Wnt
Molecular Formula
C20H17FO2S
Additionnal Information
Sulindac sulfide is a potent, reversible and noncompetitive inhibitor of γ42-secretase with an IC50 of 20.2 μM. It preferentially reduces Aβ42 generation, inhibits Aβ40 and Notch intracellular domain production, and can be used in Alzheimer's disease research.
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