BMS-986449
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Additionnal Information
BMS-986449 is a CELMoD molecular glue and a degrader of IKZF2/IKZF4. It redirects the E3 ubiquitin ligase Cereblon to induce the degradation of Helios and Eos in Treg cells, to enhance antitumor immunity, and shows promise for advanced solid tumor research.
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