Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Tetrabenazine

Product Specifications

CAS Number

718635-93-9

Synonyms

Ro 1-9569

Target

VMAT

Applications

Transmembrane Transporters

Molecular Formula

C19H27NO3

Additionnal Information

Tetrabenazine (Ro 1-9569) is a non-competitive inhibitor of the vesicular monoamine transporter (VMAT), with a higher selectivity for VMAT2 over VMAT1. It exhibits an IC50 of 0.3 μM for VMAT2 and 3 μM for VMAT1, and a Kd of 60 nM for VMAT2 and 9.38 nM for VMAT1. It treats Huntington’s chorea by reducing excessive dopaminergic activity and impairing monoamine storage in synaptic vesicles.

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Mouse DCTN3 shRNA Plasmid
abx974349-01 150 µg

Mouse DCTN3 shRNA Plasmid

Sign In for Pricing
View Details
Mouse DCTN3 shRNA Plasmid
abx974349-02 300 µg

Mouse DCTN3 shRNA Plasmid

Sign In for Pricing
View Details
Ion Selective Electrode Std Water Hardness Std 1000ppm CaCO3 - 500ML
ISEWH5 500 mL

Ion Selective Electrode Std Water Hardness Std 1000ppm CaCO3 - 500ML

Sign In for Pricing
View Details
Human NAP1L3 Protein Lysate 20ug
IHUNAP1L3PLLY20UG 20 µg

Human NAP1L3 Protein Lysate 20ug

Sign In for Pricing
View Details
5-Amino-N, N'-bis[2-hydroxy-1- (hydroxymethyl) ethyl]-2,4,6-triiodo-1,3-benzenedicarboxamide-d8
434981 1 mg

5-Amino-N, N'-bis[2-hydroxy-1- (hydroxymethyl) ethyl]-2,4,6-triiodo-1,3-benzenedicarboxamide-d8

Sign In for Pricing
View Details
Mouse Galectin 4 (GAL4) Antibody Pair Kit (with Standard)
MBS2098755-01 5x 96 Tests

Mouse Galectin 4 (GAL4) Antibody Pair Kit (with Standard)

Sign In for Pricing
View Details