Sivelestat sodium

Product Specifications

CAS Number

150374-95-1

Synonyms

ONO-5046, Sodium sivelestat, LY544349 sodium

Target

Serine Protease

Applications

Proteases

Molecular Formula

C20H21N2NaO7S

Additionnal Information

Sivelestat sodium (ONO-5046, Sodium sivelestat, LY544349 sodium) is a potent, specific, and intravenously active inhibitor of neutrophil elastase with an IC50 value of 44 nm. It is a useful agent for studying the roles of neutrophil elastase in animal disease models such as emphysema, adult respiratory distress syndrome, septic shock and disseminated intravascular coagulation in COVID-19.