Pexidartinib Hydrochloride
Product Specifications
CAS Number
2040295-03-0
Synonyms
PLX-3397 hydrochloride
Target
CSF-1R
Applications
Protein Tyrosine Kinase
Molecular Formula
C20H15ClF3N5.ClH
Additionnal Information
Pexidartinib Hydrochloride is an oral tyrosine kinase inhibitor of colony-stimulating factor 1 receptor (CSF1R) . It significantly reduces macrophage levels in adipose tissue without altering overall myeloid cell counts in mice. It also induces developmental and immunotoxic effects in zebrafish embryos by hyperactivating Wnt signaling.
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
DNAG-100 100 Tests
QuantiChrom™ β-N-Acetylglucosaminidase Assay Kit
Sign In for Pricing
View Details 
