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SKLB-11A

Product Specifications

CAS Number

433953-86-7

Target

Sirtuin

Applications

DNA Damage/DNA Repair

Molecular Formula

C19H15FN4O2

Additionnal Information

SKLB-11A is a selective, first-in-class allosteric activator of SIRT3 that binds with a Kd of 4.7 μM and enhances its deacetylase activity with EC50 of 21.95 μM. It improves cardiac function and alleviates myocardial damage in vivo.

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