SKLB-11A
Product Specifications
CAS Number
433953-86-7
Target
Sirtuin
Applications
DNA Damage/DNA Repair
Molecular Formula
C19H15FN4O2
Additionnal Information
SKLB-11A is a selective, first-in-class allosteric activator of SIRT3 that binds with a Kd of 4.7 μM and enhances its deacetylase activity with EC50 of 21.95 μM. It improves cardiac function and alleviates myocardial damage in vivo.
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