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2-APQC

Product Specifications

CAS Number

500271-63-6

Target

Sirtuin

Applications

DNA Damage/DNA Repair

Molecular Formula

C23H24FN5O

Additionnal Information

2-APQC is a potent activator of SIRT3 with a Kd value of 2.756 μM. It alleviates myocardial hypertrophy and fibrosis by regulating mitochondrial homeostasis, exhibiting promising cardioprotective potential in vitro and in vivo. It may serve as a potential candidate for future heart failure (HF) therapeutics.
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