What is the catalog number for LYG-409?

The catalog number for LYG-409 is E5877-1g.

What sizes are available for LYG-409?

LYG-409 is available in the following size(s): 1 g.

LYG-409 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures LYG-409?

LYG-409 is manufactured by Bimake.

What is the estimated delivery time for LYG-409?

Estimated delivery time for LYG-409 is approximately 15 business day(s), depending on your location.

LYG-409

Product Specifications

CAS Number

3053857-55-6

Target

E3 Ligase

Applications

Ubiquitin

Molecular Formula

C25H20F3N3O6

Additionnal Information

LYG-409 is a potent, selective, and orally bioavailable degrader of GSPT1, with a DC50 of 7.87 nM. It exhibits strong antiproliferative activity in KG-1 cells with an IC50 of 9.50 nM and demonstrates significant antitumor efficacy in vivo in models of acute myeloid leukemia and prostate cancer.