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INT-767

Product Specifications

CAS Number

1000403-03-1

Target

FXR

Applications

Metabolism

Molecular Formula

C25H44O6S.Na

Additionnal Information

INT-767 is a dual agonist of farnesoid X receptor (FXR) /TGR5 with an EC50 of 0.033 μM and 0.67 μM, respectively. It significantly improves serum liver enzymes, hepatic inflammation, and biliary fibrosis, while inducing bile flow and biliary HCO3− output, making it a promising tool for chronic cholangiopathy research.

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