VAV1 degrader-3
Product Specifications
CAS Number
3050683-38-7
Synonyms
MRT-6160
Molecular Formula
C22H17ClN2O3
Additionnal Information
VAV1 degrader-3 (MRT-6160) is an orally active molecular glue degrader of VAV1 with a DC50 of 7 nM. It suppresses immune activation, proliferation, and cytokine production, inhibiting disease progression in inflammatory and autoimmune models like encephalomyelitis (EAE) and Collagen-induced arthritis (CIA) .
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