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KN-93 hydrochloride

Product Specifications

CAS Number

1956426-56-4

Target

CaMK

Applications

Neuronal Signaling

Molecular Formula

C26H29ClN2O4S.ClH

Additionnal Information

KN-93 hydrochloride is a methoxybenzenesulfonamide derivative that inhibits Ca2+/calmodulin-dependent protein kinase II (CaMKII) with a Ki of 0.37 μM. It reduces dopamine (DA) production by influencing the reaction rate of tyrosine hydroxylase (TH), leading to decreased Ca (2+) -mediated phosphorylation of the TH protein.

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