What is the catalog number for PU139?

The catalog number for PU139 is E5829-5mg.

What sizes are available for PU139?

PU139 is available in the following size(s): 5 mg.

PU139 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures PU139?

PU139 is manufactured by Bimake.

What is the estimated delivery time for PU139?

Estimated delivery time for PU139 is approximately 15 business day(s), depending on your location.

PU139

Product Specifications

CAS Number

158093-65-3

Target

Histone Acetyltransferase

Applications

Epigenetics

Molecular Formula

C12H7FN2OS

Additionnal Information

PU139 is a potent inhibitor of pan-histone acetyltransferase (HAT) that blocks Gcn5, PCAF, CBP, and p300 with IC50 values of 8.39 μM, 9.74 μM, 2.49 μM, and 5.35 μM, respectively. It significantly impairs Smp14 promoter activity, suggesting that targeting SmGCN5 and SmCBP1 is a novel strategy to control S. mansoni egg development, it also exhibits anticancer activity.