Propranolol
Product Specifications
CAS Number
525-66-6
Target
Adrenergic Receptor
Applications
Neuronal Signaling
Molecular Formula
C16H21NO2
Additionnal Information
Propranolol is a non-selective antagonist of β-adrenergic receptors (βAR), with Ki values of 1.8 nM for β1AR and 0.8 nM for β2AR, effectively lowering cAMP levels and activating the MAPK pathway downstream of βARs. It is an effective treatment for infantile hemangiomas (IHs), where it induces antiproliferative and antisurvival effects on hemangioma stem cells (HemSCs) .
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