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MASM7

Product Specifications

CAS Number

920868-45-7

Target

Mitochondrial Metabolism

Applications

Metabolism

Molecular Formula

C22H23N5O2S2

Additionnal Information

MASM7 is an activator of mitofusins that promotes mitochondrial fusion through mitofusins. It increases mitochondrial AR in MEFs in a concentration-dependent manner, with an EC50 value of 75 nM. MASM7 also directly binds to the HR2 domain of MFN2 with a dissociation constant (Kd) of 1.1 μM, effectively activating MFN2 or MFN to induce fusion.

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