Fedratinib hydrochloride hydrate
Product Specifications
CAS Number
1374744-69-0
Synonyms
TG-101348 hydrochloride hydrate, SAR 302503 hydrochloride hydrate
Target
JAK
Applications
Angiogenesis
Molecular Formula
C27H36N6O3S.2ClH.H2O
Additionnal Information
Fedratinib hydrochloride hydrate (TG-101348 hydrochloride hydrate, SAR 302503 hydrochloride hydrate) is a small-molecule, ATP-competitive inhibitor of JAK2 with IC50s of 3 nM for both JAK2 and JAK2V617F kinase. It induces cancer cell apoptosis and has potential for efficacious treatment of JAK2V617F-associated myeloproliferative disease.
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