Dactolisib Tosylate
Product Specifications
CAS Number
1028385-32-1
Synonyms
BEZ235 Tosylate, NVP-BEZ 235 Tosylate
Target
PI3K
Applications
PI3K/Akt/mTOR
Molecular Formula
C30H23N5O.C7H8O3S
Additionnal Information
Dactolisib Tosylate (BEZ235 Tosylate, NVP-BEZ 235 Tosylate) is an imidazo[4,5-c]quinoline derivative and dual inhibitor of PI3K/mTOR with IC50 values of 4, 75, 7, and 5 nM for PI3Kα, β, γ, and δ, respectively. It blocks mTORC1/mTORC2 and demonstrates potent antitumor activity in experimental cancer models.
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