Exatecan
Product Specifications
CAS Number
171335-80-1
Synonyms
DX-8951
Target
Topoisomerase
Applications
DNA Damage/DNA Repair
Molecular Formula
C24H22FN3O4
Additionnal Information
Exatecan (DX-8951), is a water-soluble derivative of camptothecin. It acts as an inhibitor of DNA topoisomerase I with an IC50 value of 1.906 μM. It demonstrates potent antitumor effects and triggers apoptotic cell death after treatment in human pancreatic cancer cells.
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
248943-AP 100 µL
MSH2 (mutS Homolog 2, Colon Cancer, nonpolyposis Type 1 (E. coli), COCA1, FCC1, HNPCC, HNPCC1, LCFS2) (AP) discontinued
Sign In for Pricing
View Details 