Polyinosinic-polycytidylic acid sodium
Product Specifications
CAS Number
42424-50-0
Synonyms
Poly (I:C) sodium
Target
TLR
Applications
Immunology & Inflammation
Molecular Formula
(C10H13N4O8P) x. (C9H14N3O8P) x.xNa
Additionnal Information
Polyinosinic-polycytidylic acid sodium (Poly (I:C) sodium) is a synthetic double-stranded RNA (dsRNA) analogue that activates the MDA-5 receptor in the cytoplasm and TLR3 in endosomal compartments. This activation promotes the production of type I interferons and induces apoptosis in cancer cells, particularly those that lack protective anti-apoptotic mechanisms like Bcl-xL.
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