What is the catalog number for Cl-amidine hydrochloride?

The catalog number for Cl-amidine hydrochloride is E4995-100mg.

What sizes are available for Cl-amidine hydrochloride?

Cl-amidine hydrochloride is available in the following size(s): 100 mg.

Is Cl-amidine hydrochloride in stock?

Cl-amidine hydrochloride is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Cl-amidine hydrochloride?

Cl-amidine hydrochloride is manufactured by Bimake.

What is the estimated delivery time for Cl-amidine hydrochloride?

Estimated delivery time for Cl-amidine hydrochloride is approximately 15 business day(s), depending on your location.

Cl-amidine hydrochloride

Product Specifications

CAS Number

1373232-26-8

Target

PAD

Applications

Metabolism

Molecular Formula

C14H19ClN4O2.ClH

Additionnal Information

Cl-amidine hydrochloride is an orally active peptidylarginine deminase (PAD) inhibitor, with IC50 values of 0.8 μM, 6.2 μM and 5.9 μM for PAD1, PAD3, and PAD4, respectively. Cl-amidine hydrochloride induces apoptosis in cancer cells. Cl-amidine hydrochloride induces microRNA (miR) -16 (miRNA-16, microRNA-16) expression and causes cell cycle arrest. Cl-Amidine hydrochloride prevents histone 3 citrullination and neutrophil extracellular trap formation, and improves survival in a murine sepsis model[1][2][3][4][5].