Mozavaptan (hydrochloride)
Product Specifications
CAS Number
138470-70-9
Synonyms
OPC 31260 HCl
Target
Vasopressin Receptor
Applications
GPCR & G Protein
Molecular Formula
C27H29N3O2.ClH
Additionnal Information
Mozavaptan hydrochloride (OPC 31260 HCl), a benzazepine derivative is a potent, selective, competitive, and orally active antagonist of vasopressin V2 receptor with an IC50 value of 14 nM. Mozavaptan hydrochloride shows ~85-fold selectivity for V2 receptor over V1 receptor. Mozavaptan hydrochloride has the potential for hyponatremia, syndrome of inappropriate antidiuretic hormone (SIADH), and congestive heart failure treatment.
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