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Baclofen hydrochloride

Product Specifications

CAS Number

28311-31-1

Target

GABA Receptor

Applications

Neuronal Signaling

Molecular Formula

C10H12ClNO2.ClH

Additionnal Information

Baclofen hydrochloride is an agonist of the GABAB receptor that mimics the action of GABA, leading to slow presynaptic inhibition via the GABAB receptor. It improves the function of the ubiquitin-proteasome system (UPS) and enhances cell survival in both in vitro and in vivo models of Huntington's disease (HD) .

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