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Cariprazine

Product Specifications

CAS Number

839712-12-8

Synonyms

RGH-188, MP-214

Target

Dopamine Receptor

Applications

Neuronal Signaling

Molecular Formula

C21H32Cl2N4O

Additionnal Information

Cariprazine (RGH-188, MP-214) acts primarily as a partial agonist at dopamine receptors, with pKi values of 10.07 for D3, 9.16 for D2L, and 9.31 for D2S receptors. It also acts as an antagonist forserotonin receptors, with pKi of 9.24, 8.59, 7.73, and 6.87 for5-HT2B,5-HT1A, 5-HT2A, and 5-HT2C receptors, respectively.

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