Estramustine
Product Specifications
CAS Number
2998-57-4
Synonyms
NSC-89201, LEO275
Target
Microtubule Associated
Applications
Cytoskeletal Signaling
Molecular Formula
C23H31Cl2NO3
Additionnal Information
Estramustine (NSC-89201, LEO275) is used to treat hormone-resistant prostate cancer and stabilize microtubule dynamics. It acts as an anti-mitotic and anti-microtubule agent and disrupts microtubule disassembly. It inhibits the binding of MAPs 1 and 2 to taxol-stabilized microtubules, hinders microtubule assembly, and promotes the disassembly of MAP-2-associated microtubules.
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