What is the catalog number for HS-10296 hydrochloride?

The catalog number for HS-10296 hydrochloride is E4886-25mg.

What sizes are available for HS-10296 hydrochloride?

HS-10296 hydrochloride is available in the following size(s): 25 mg.

Is HS-10296 hydrochloride in stock?

HS-10296 hydrochloride is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures HS-10296 hydrochloride?

HS-10296 hydrochloride is manufactured by Bimake.

What is the estimated delivery time for HS-10296 hydrochloride?

Estimated delivery time for HS-10296 hydrochloride is approximately 15 business day(s), depending on your location.

HS-10296 hydrochloride

Product Specifications

CAS Number

2134096-03-8

Synonyms

Almonertinib (hydrochloride), HS-10296 HCl

Target

EGFR

Applications

Protein Tyrosine Kinase

Molecular Formula

C30H35N7O2.ClH

Additionnal Information

HS-10296 hydrochloride (Almonertinib (hydrochloride), HS-10296 HCl) is an irreversible, third-generation inhibitor of EGFR tyrosine kinase that demonstrates high selectivity for EGFR-sensitizing mutations, T790M resistance mutation. It exhibits inhibitory activity against T790M, T790M/L858R, and T790M/Del19, with IC50 of 0.37 nM, 0.29 nM, and 0.21 nM, respectively. It also exhibits anti-tumor activity.