Tazemetostat hydrobromide
Product Specifications
CAS Number
1467052-75-0
Synonyms
EPZ-6438 hydrobromide
Target
EZH1/2
Applications
Epigenetics
Molecular Formula
C34H44N4O4.BrH
Additionnal Information
Tazemetostat hydrobromide (EPZ-6438 hydrobromide) is a potent, selective, and orally available inhibitor of EZH2. It inhibits EZH2 with IC50 values of 11 and 16 nM in peptide assay and nucleosome assay, respectively. Tazemetostat hydrobromide also inhibits EZH1 with an IC50 of 392 nM.
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