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Tacrine

Product Specifications

CAS Number

321-64-2

Target

AChR

Applications

Neuronal Signaling

Molecular Formula

C13H14N2

Additionnal Information

Tacrine is a potent acetylcholinesterase (AChE) inhibitor. It inhibits acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) with an IC50 of 77 nM and 69 nM, respectively. It is used in the treatment of Alzheimer's disease (AD), also poisoning topoisomerases and inhibiting in vivo (mitochondrial) mtDNA synthesis.

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