Aprocitentan
Product Specifications
CAS Number
1103522-45-7
Synonyms
ACT-132577
Target
Endothelin Receptor
Applications
GPCR & G Protein
Molecular Formula
C16H14Br2N6O4S
Additionnal Information
Aprocitentan (ACT-132577) is a pharmacologically active metabolite of Macitentan. Aprocitentan is an orally active dual antagonist of ETA/ETB with IC50 values of 3.4 nM and 987 nM, and pA2 values of 6.7 and 5.5, respectively.
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS9440323-01 0.1 mL (Biotin)
ERLIN1 Polyclonal Conjugated Antibody
Sign In for Pricing
View Details